spo0M [2017-8-11 16:0:3]

sporulation-control gene

locus: BSU08760

pI: 4.28

mw: 29.56 kDa

protein length: 258 aa

gene length: 774 bp

function: sporulation

product: unknown

essential: no

synonyms: ygaI

Genomic Context

categories

• [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.3|Sporulation/ other]
• [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.2|Cell envelope stress proteins (controlled by SigM, V, W, X, Y)]

Gene

Coordinates: 953,373 → 954,149

Phenotypes of a mutant

• Blocked at stage zero of [SW|sporulation] and is susceptible to lysis during vegetative growth [Pubmed|9795118]

The protein

Protein family

• spo0M family (according to Swiss-Prot)

Effectors of protein activity

• the protein is degraded by the [protein|4E7B9426CED372AA8A321A147116A3A589FBF20C|FtsH] metalloprotease [Pubmed|22142536]

Structure

• [PDB|5CL2] [Pubmed|26625291]

[SW|Localization]

• scattered distribution pattern in cells, appearing near the cell poles and the septum region [pubmed|28234965]

Expression and Regulation

Operons

• genes: [gene|86BEE9B4DEA83B3B8EFC52EFDDC1F62314FC4291|spo0M]
  description: [Pubmed|9795118]

  sigma factors

  • [protein|DC3449D5F195E5C2E9E14FEC95396C8F1FDF73B4|SigH]: sigma factor, [Pubmed|9795118], in [regulon|DC3449D5F195E5C2E9E14FEC95396C8F1FDF73B4|SigH regulon]
  • [protein|3D974DD2967C7F8FD4E3C2AF42617B8AE9F0296D|SigW]: sigma factor, [Pubmed|11866510], in [regulon|3D974DD2967C7F8FD4E3C2AF42617B8AE9F0296D|SigW regulon]

  additional information

  • the protein is degraded by the [protein|search|FtsH] metalloprotease [PubMed|22142536]

References

Reviews

• 28577219

Original publications

• 9795118,11866510,22142536,26625291,28234965